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位置: 首页> 品牌> Sigma-Aldrich> Anti-Phospho-LMNA-S22 antibody produced in rabbit

Anti-Phospho-LMNA-S22 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB5700450
包装型号
规格纯度
价格
4713.83 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
Anti-Phospho-LMNA-S22 antibody produced in rabbit
CDDC
CMD1A
LGMD1B
LFP
EMD2
LMNL1
LMN1
FPLD2
IDC
FPL
FPLD
HGPS
LMNA
LMNC
LDP1
CDCD1
CMT2B1
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome.

免疫原

A synthetic phosphorylated peptide around S22 of human LMNA (NP_005563.1).

外形

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

储存及稳定性

Store at -20℃. Avoid freeze / thaw cycles.

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 62-74
species reactivity human, rat
浓度 1.59 mg/ml
technique(s) immunoprecipitation (IP): 1:50-1:100
western blot: 1:500-1:2000
UniProt登记号 P02545
运输 wet ice
储存温度 ?20℃
Gene Information human ... LMNA(4000)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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