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位置: 首页> 品牌> Sigma-Aldrich> Anti-phospho-GRIN1 (pSer896) antibody produced in rabbit

Anti-phospho-GRIN1 (pSer896) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB4300083
规格纯度
affinity isolated antibody
价格
5001.78 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
Anti-phospho-GRIN1 (pSer 896) antibody produced in rabbit
Anti-NMDA1 antibody produced in rabbit
Anti-NR1 antibody produced in rabbit
Anti-glutamate receptor, ionotropic, N-methyl D-aspartate 1 antibody produced in rabbit
Anti-NMDAR1 antibody produced in rabbit
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

免疫原

Peptide sequence around phosphorylation site of serine 896 (R-R-S(p)-S-K), according to the protein GRIN1.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

目标描述

NMDA receptors are members of the ionotropic class of glutamate receptors, which also includes Kainate and AMPA receptors. NMDA receptors consist of NR1 subunits combined with one or more NR2 (A-D) or NR3 (A-B) subunits. The ligand-gated channel is permeable to cations including Ca2+, and at resting membrane potentials NMDA receptors are inactive due to a voltage-dependent blockade of the channel pore by Mg2+. NMDA receptor activation, which requires binding of glutamate and glycine, leads to an influx of Ca2+ into the postsynaptic region where it activates several signaling cascades, including pathways leading to the induction of long-term potentiation (LTP) and depression (LTD). NMDA receptors have a critical role in excitatory synaptic transmission and plasticity in the CNS. They govern a rangeof physiological conditions including neurological disorders caused by excitotoxic neuronal injury, psychiatric disorders and neuropathic pain syndromes.

外形

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号 MFCD00282329
NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 ~120 kDa
species reactivity human, rat, mouse
浓度 1 mg/mL
technique(s) western blot: 1:500-1:1000
同位素/亚型 IgG
免疫原序列 (R-R-SP-S-K)
NCBI登记号 NP_000823.4
UniProt登记号 Q05586
运输 wet ice
储存温度 ?20℃
Gene Information human ... GRIN1(2902)

安全信息

储存分类代码 10 - Combustible liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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