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位置: 首页> 品牌> Sigma-Aldrich> Anti-Phospho-FADD-S194 antibody produced in rabbit

Anti-Phospho-FADD-S194 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB5700564
包装型号
规格纯度
价格
4713.83 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
Anti-Phospho-FADD-S194 antibody produced in rabbit
FADD
MORT1
GIG3
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development.

免疫原

A phospho synthetic peptide corresponding to residues surrounding S194 of human FADD.

外形

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

储存及稳定性

Store at -20℃. Avoid freeze / thaw cycles.

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 23
species reactivity human
浓度 3.67 mg/ml
technique(s) western blot: 1:500-1:2000
UniProt登记号 Q13158
运输 wet ice
储存温度 ?20℃
Gene Information human ... FADD(8772)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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