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位置: 首页> 品牌> Sigma-Aldrich> Anti-Phospho-Erk1/2-T202/Y204 antibody produced in rabbit

Anti-Phospho-Erk1/2-T202/Y204 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB5701896
包装型号
规格纯度
价格
4266.29 *本价格含增值税费
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半岛bd体育手机客户端 名称:
Anti-Phospho-Erk1/2-T202/Y204 antibody produced in rabbit
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jan 2014]

免疫原

A phospho specific peptide corresponding to residues surrounding T202/Y204+T185/Y187 of human ERK1+ERK2.

外形

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
antibody product type primary antibodies
克隆 polyclonal
形式 liquid
species reactivity human, mouse, rat
浓度 2.42 mg/mL
technique(s) western blot: 1:500-1:2000
UniProt登记号 P28482/P2736
运输 wet ice
储存温度 ?20℃

安全信息

闪点(F) Not applicable
闪点(C) Not applicable

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