半岛bd体育手机客户端 说明
一般描述
This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. [provided by RefSeq, Jul 2008]
免疫原
A phospho specific peptide corresponding to residues surrounding Y221 of human CRK/CRKII
外形
Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
半岛bd体育手机客户端 性质
生物来源 | rabbit |
质量水平 | 100 |
antibody product type | primary antibodies |
克隆 | monoclonal |
形式 | liquid |
species reactivity | rat, human |
浓度 | 0.53 mg/mL |
technique(s) | western blot: 1:500-1:2000 |
UniProt登记号 | P46108 |
运输 | wet ice |
储存温度 | ?20℃ |
Gene Information | human ... CRK(1398) |
安全信息
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich