半岛bd体育手机客户端 说明

一般描述

Cortactin is an actin-related protein 2/3 (Arp2/3) complex–activating and filamentous (F)-actin–binding protein. This protein is coded by CTTN gene that maps to human chromosome 11q13.

免疫原

The antiserum was produced against synthesized peptide derived from mouse Cortactin around the phosphorylation site of Tyr466.

Immunogen Range:441-490

应用

Anti-phospho-Cortactin (pTyr421) antibody has been used in western blotting and immunoprecipitation.

生化/生理作用

Cortactin controls Arp2/3-mediated actin polymerization. This protein also modulates aggressive cancer cell traits like tumor growth, cancer cell invasion and motility, and serum and anchorage-independent growth.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES

NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
偶联物	unconjugated
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
形式	buffered aqueous solution
分子量	antigen 61 kDa
species reactivity	human, rat, mouse
浓度	~1 mg/mL
technique(s)	ELISA: 1:20000 immunohistochemistry: 1:50-1:100 western blot: 1:500-1:1000
NCBI登记号	Q60598
UniProt登记号	Q14247
运输	wet ice
储存温度	?20℃
Gene Information	mouse ... Cttn(13043)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable