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位置: 首页> 品牌> Sigma-Aldrich> Anti-phospho-CHUK (pThr23) antibody produced in rabbit

Anti-phospho-CHUK (pThr23) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB4300106
规格纯度
affinity isolated antibody
价格
4618.16 *本价格含增值税费
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数量
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半岛bd体育手机客户端 名称:
Anti-phospho-CHUK (pThr 23) antibody produced in rabbit
Anti-IKK1 antibody produced in rabbit
Anti-IKBKA antibody produced in rabbit
Anti-IKKA antibody produced in rabbit
Anti-conserved helix-loop-helix ubiquitous kinase antibody produced in rabbit
Anti-IKK-alpha antibody produced in rabbit
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

免疫原

Peptide sequence around phosphorylation site of threonine 23 (L-G-T(p)-G-G), according to the protein CHUK.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

目标描述

Acts as part of the IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. As part of the non-canonical pathway of NF-kappa-B activation, the MAP3K14-activated CHUK/IKKA homodimer phosphorylates NFKB2/p100 associated with RelB, inducing its proteolytic processing to NFKB2/p52 and the formation of NF-kappa-B RelB-p52 complexes. Also phosphorylates NCOA3. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines.

外形

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号 MFCD02096685
NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 ~85 kDa
species reactivity rat, mouse, human
浓度 1 mg/mL
technique(s) immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
western blot: 1:500-1:1000
同位素/亚型 IgG
免疫原序列 (L-G-TP-G-G)
NCBI登记号 NP_001269.3
UniProt登记号 O15111
运输 wet ice
储存温度 ?20℃
Gene Information human ... CHUK(1147)

安全信息

储存分类代码 10 - Combustible liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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