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位置: 首页> 品牌> Sigma-Aldrich> Anti-Phospho-CDK4-T172 antibody produced in rabbit

Anti-Phospho-CDK4-T172 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB5700423
包装型号
规格纯度
价格
4713.83 *本价格含增值税费
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数量
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半岛bd体育手机客户端 名称:
Anti-Phospho-CDK4-T172 antibody produced in rabbit
CMM3
PSK-J3
CDK4
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported.

免疫原

A synthetic phosphorylated peptide around T172 of human CDK4 (NP_000066.1).

外形

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

储存及稳定性

Store at -20℃. Avoid freeze / thaw cycles.

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 20
33
species reactivity rat, mouse, human
浓度 1.45 mg/ml
technique(s) western blot: 1:500-1:2000
UniProt登记号 P11802
运输 wet ice
储存温度 ?20℃
Gene Information human ... CDK4(1019)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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