Anti-Periostin Antibody (C-term)

半岛bd体育手机客户端 说明

一般描述

Periostin, also known as PN, or Osteoblast-specific factor 2 (OSF-2), and encoded by the gene POSTN/OSF2, is a secreted extracellular matrix protein that appears to be involved in inducing cell attachment and spreading as well as cell adhesion. In bone, Periostin enhances mineralization and assists in the incorporation of BMP1 protein into the fibronectin extracellular matrix of connective tissues. Periostin is preferentially expressed in periosteum and periodontal ligaments but can also be found expressed in developing heart and other tissues. Periostin is also over expressed in many cancers where is contributes to a growth-supportive role for such cancers and also aids in chemoresistance for cancers cells through the activation of the PI3K/Akt/surviving pathway.

特异性

This antibody detects a subset of splice variants of Periostin.

免疫原

A 188-amino acid bacterial fusion protein from the C-terminal region of mouse periostin.
Epitope: C-terminus

应用

Research Category
Cell Structure
Anti-Periostin Antibody (C-term) is an antibody against Periostin (C-term) for use in western blotting.
Research Sub Category
Adhesion (CAMs)

质量

Evaluated by Western Blotting in mouse lung tissue lysate.

Western Blotting Analysis: 1.0 ?g/mL of this antibody detected Periostin in 10 ?g of mouse lung tissue lysate.

目标描述

~80-85 kDa observed. Multiple splice variants detected.

外形

Affinity purified
Purified rabbit polyclonal in buffer containing PBS with 0.05% sodium azide.

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss	32160702
NACRES	NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
纯化方式	affinity chromatography
species reactivity	mouse
浓度	1 mg/mL
technique(s)	western blot: suitable
NCBI登记号	NP_001185694
UniProt登记号	Q62009
运输	wet ice

安全信息

储存分类代码	10 - Combustible liquids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable