Anti-Perilipin-3, C-terminus Antibody

半岛bd体育手机客户端 说明

一般描述

Perilipin-3, also known as Cargo selection protein TIP47, or Placental protein 17, PP17, 47 kDa mannose 6-phosphate receptor-binding protein, 47 kDa MPR-binding protein, also known as Mannose-6-phosphate receptor-binding protein 1, and encoded by the gene PLIN3/M6prbp1/Tip47, is a peripheral membrane protein that is required for the transport of mannose 6-phosphate receptors (MPR) from the endosomes to the trans-Golgi network. Perilipin 3 is part of the Perilipin family of proteins which are proteins that decorate the surface of cytosolic lipid droplets and play important roles in lipid metabolism. Cytosolic lipid droplets are now recognized as multifunctional organelles that, among other things, can accumulate in leukocytes under various inflammatory conditions. Perilipin-3 seems to play a critical role in the formation of lipid droplets and production of the the prostaglandin PGE2 an important inflammatory compound.

免疫原

Linear peptide corresponding to the C-terminus of mouse Perilipin-3, C-terminus.
Epitope: C-terminus

应用

Immunocytochemistry Analysis: A representative lot detected Perilipin-3, C-terminus in OP9 cells (Skinner, J. R., et al. (2009). J Biol Chem. 284(45):30941-30948).
Research Category
Signaling
Research Sub Category
Signaling Neuroscience
This Anti-Perilipin-3 antibody, C-terminus is validated for use in western blotting & ICC for the detection of Perilipin-3.

质量

Evaluated by Western Blotting in NIH/3T3-L1 cell lysate.

Western Blotting Analysis: A 1:1,000 dilution of this antibody detected Perilipin-3, C-terminus in 10 ?g of NIH/3T3-L1 cell lysate.

目标描述

~ 52 kDa observed

外形

Affinity purified
Purified rabbit polyclonal in buffer containing PBS without preservatives with 10% glycerol.

储存及稳定性

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss	32160702
NACRES	NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
纯化方式	affinity chromatography
species reactivity	mouse
technique(s)	immunocytochemistry: suitable western blot: suitable
NCBI登记号	NP_080112
UniProt登记号	Q9DBG5
运输	wet ice

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable