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位置: 首页> 品牌> Sigma-Aldrich> Anti-Pcsk1n (N-terminal) antibody produced in rabbit

Anti-Pcsk1n (N-terminal) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB2109119
规格纯度
affinity isolated antibody
价格
5258.35 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Anti-Pcsk1n (N-terminal) antibody produced in rabbit
Saas
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Pcsk1n may function in the control of the neuroendocrine secretory pathway. It is proposed to be a specific endogenous inhibitor of PCSK1. ProSAAS and Big PEN-LEN, both containing the C-terminal inhibitory domain, but not the processed peptides reduce PCSK1 activity in the endoplasmic reticulum and Golgi. It reduces the activity of the 87 kDa form but not the autocatalytically derived 65 kDa form of PCSK1. Subsequent processing of proSAAS may eliminate the inhibition. Slows down convertase-mediated processing of proopiomelanocortin and proenkephalin. Pcsk1n may control the intracellular timing of PCSK1 rather than its total level of activity.

免疫原

Synthetic peptide directed towards the N-terminal region of Rat Pcsk1n

序列

Synthetic peptide located within the following region: STPLRLRRAVPRGEAAGAVQELARALAHLLEAERQERARAEAQEAEDQQA

外形

Supplied at 0.5 mg/ml in phosphate-buffered saline, 0.09% sodium azide

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

半岛bd体育手机客户端 性质

生物来源 rabbit
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 28 kDa
species reactivity (predicted by homology) rat, canine, human, mouse, guinea pig, bovine
浓度 0.5 mg/mL
technique(s) western blot: 1 μg/mL
NCBI登记号 NM_019279
运输 wet ice
储存温度 ?20℃
Gene Information human ... PCSK1N(27344)

安全信息

储存分类代码 10 - Combustible liquids
WGK nwg
闪点(F) Not applicable
闪点(C) Not applicable

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