Anti-PAX6 antibody produced in mouse

半岛bd体育手机客户端 说明

一般描述

The paired box 6 (PAX6) gene with 14 exons, is mapped to human chromosome 11p13. The encoded protein belongs to the paired-domain Pax family. PAX6 is a 422 amino acids protein, generally expressed in the developing eye, both in neuroectoderm and surface ectoderm. It is also present in the adult eye.

免疫原

PAX6 (NP_000271.1, 1 a.a. ~ 422 a.a) full-length human protein.

Sequence
MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPPVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTSTGLISPGVSVPVQVPGSEPDMSQYWPRLQ

生化/生理作用

Paired box 6 (PAX6) is a highly conserved transcriptional regulator involved in oculogenesis. In addition, it is also implicated in maintenance of adult eye. Mutation in the gene leads to the development of aniridia in humans and small eyes in rats.

外形

Solution in phosphate buffered saline, pH 7.4

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

半岛bd体育手机客户端 性质

质量水平	100
生物来源	mouse
偶联物	unconjugated
抗体形式	purified immunoglobulin
antibody product type	primary antibodies
克隆	polyclonal
形式	buffered aqueous solution
分子量	antigen ~46.7 kDa
species reactivity	human
technique(s)	western blot: 1 μg/mL
NCBI登记号	NM_000280.2
UniProt登记号	P26367
运输	dry ice
储存温度	?20℃
Gene Information	human ... PAX6(5080)

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable