Anti-Pan-QKI Antibody, clone N147/6

半岛bd体育手机客户端 说明

一般描述

QKI is also called Protein Quaking or HqkI. QKI is an RNA-binding protein that plays a central role in myelinization. QKI acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation, and is itself, regulated by alternative splicing. QKI is expressed in the frontal cortex of brain, but is shown to be down-regulated in the brain of schizophrenic patients.

特异性

This antibody demonstrates cross reactivity against QKI-6, QKI-7, and QKI-7b (Prof. J. Trimmer, University of California, Davis.).

免疫原

Recombinant protein corresponding to human Pan-QKI.

应用

Anti-Pan-QKI Antibody, clone N147/6 is a highly specific mouse monoclonal antibody & that targets QKI & has been tested in western blotting.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Pan-QKI in human frontal cortex.

Immunohistochemistry Analysis: A representative lot detected Pan-QKI in rat hippocampus tissue (Prof. J. Trimmer, University of California, Davis.).

Western Blotting Analysis: 2 ?g/mL from a representative lot detected Pan-QKI in 10 ?g of rat brain tissue.

Western Blotting Analysis: 2 ?g/mL from a representative lot detected Pan-QKI in 10 ?g of mouse brain membrane tissue.

Western Blotting Analysis: A representative lot detected Pan-QKI in RBM cell lysates and in COS cell lysates transfected with QKI-5, QKI-6, QKI-7, and QKI-7b (Prof. J. Trimmer, University of Califorina, Davis.).
Research Category
Neuroscience
Research Sub Category
Developmental Neuroscience

质量

Evaluated by Western Blotting in rat brain membrane tissue lysate.

Western Blotting Analysis: 2 ?g/mL of this antibody detected Pan-QKI in 10 ?g of rat brain membrane tissue lysate.

目标描述

~36-40 kDa observed. Uniprot describes six isoforms observed between 35-38 kDa Uncharacterized band(s) may be observed in some cell lysates.

外形

Purified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Format: Purified
Protein G Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
Rat brain membrane tissue lysate.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss	32160702
NACRES	NA.41

半岛bd体育手机客户端 性质

质量水平	100
生物来源	mouse
抗体形式	purified immunoglobulin
antibody product type	primary antibodies
克隆	N147/6, monoclonal
species reactivity	mouse, rat, human
technique(s)	western blot: suitable
同位素/亚型	IgG2bκ
NCBI登记号	NP_006766
UniProt登记号	Q96PU8
运输	wet ice
Gene Information	human ... QKI(9444)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable