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位置: 首页> 品牌> Sigma-Aldrich> Anti-ORP150/GRP170/HSP12A antibody produced in rabbit

Anti-ORP150/GRP170/HSP12A antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB5700908
包装型号
规格纯度
价格
4668.88 *本价格含增值税费
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半岛bd体育手机客户端 名称:
Anti-ORP150/GRP170/HSP12A antibody produced in rabbit
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

The protein encoded by this gene belongs to the heat shock protein 70 family. This gene uses alternative transcription start sites. A cis-acting segment found in the 5' UTR is involved in stress-dependent induction, resulting in the accumulation of this protein in the endoplasmic reticulum (ER) under hypoxic conditions. The protein encoded by this gene is thought to play an important role in protein folding and secretion in the ER. Since suppression of the protein is associated with accelerated apoptosis, it is also suggested to have an important cytoprotective role in hypoxia-induced cellular perturbation. This protein has been shown to be up-regulated in tumors, especially in breast tumors, and thus it is associated with tumor invasiveness. This gene also has an alternative translation initiation site, resulting in a protein that lacks the N-terminal signal peptide. This signal peptide-lacking protein, which is only 3 amino acids shorter than the mature protein in the ER, is thought to have a housekeeping function in the cytosol. In rat, this protein localizes to both the ER by a carboxy-terminal peptide sequence and to mitochondria by an amino-terminal targeting signal. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

免疫原

A synthesized peptide derived from human ORP150/GRP170/HSP12A

外形

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
antibody product type primary antibodies
克隆 monoclonal
形式 liquid
species reactivity human, mouse, rat
浓度 0.15 mg/mL
technique(s) immunohistochemistry: 1:50-1:200
western blot: 1:5000-1:10000
UniProt登记号 Q9Y4L1
运输 wet ice
储存温度 ?20℃
Gene Information human ... HYOU1(10525)

安全信息

闪点(F) Not applicable
闪点(C) Not applicable

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