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位置: 首页> 品牌> Sigma-Aldrich> Anti-Olig-2 Antibody

Anti-Olig-2 Antibody

品牌
Sigma-Aldrich
货号
ABN899
规格纯度
from rabbit, purified by affinity chromatography
价格
7029.8 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Anti-Olig-2 Antibody
Oligodendrocyte transcription factor 2, bHLHe19, Olg-2, Oligo2, RACK17, RK17
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Oligodendrocyte transcription factor 2 (UniProt Q9EQW6; also known as bHLHe19, Olg-2, Oligo2, RACK17, RK17) is encoded by the Olig2 (also known as Bhlhb1) gene (Gene ID 50913) in murine species. Olig2 is a basic helix-loop-helix (bHLH) transcription factor expressed in a spinal cord ventricular zone domain where it mediates the sequential generation of motoneurons and oligodendrocytes during embryogenesis. Olig2 also functions as an anti-neurogenic factor in pMN progenitors at early time points to sustain the cycling progenitor pool. The anti-neurogenicity of Olig2 is also responsible for its role in tumorigenesis, especially in brain tumors and leukemia. Due to its expression in glioblastoma and other diffuse gliomas, Olig2 is a useful diagnostic marker of these brain tumors.

免疫原

KLH-conjugated linear peptide corresponding to a sequence in the N-terminal region of mouse Olig-2.

应用

Anti-Olig-2 Antibody is an antibody against Olig-2 for use in Western Blotting, Immunoprecipitation, Immunocytochemistry, Immunohistochemistry (Paraffin).
Immunoprecipitation Analysis: 10 ?g from a representative lot immunoprecipitated Olig-2 in 500 ?g of mouse brain tissue lysate.
Immunohistochemistry Analysis: An 1:500 dilution from a representative lot detected Olig-2 in rat hindbrain tissue sections.
Immunocytochemistry Analysis: An 1:500 dilution from a representative lot detected Olig-2 in PC12 cells.

质量

Evaluated by Western Blotting in mouse brain tissue lysate.

Western Blotting Analysis: 1.0 ?g/mL of this antibody detected Olig-2 in 10 ?g of mouse brain tissue lysate.

目标描述

~37 kDa observed. 32.40 kDa calculated.

联系

Replaces: AB15328

外形

Affinity purified
Purified rabbit polyclonal antibody in PBS and 0.1 % sodium azide.

其他说明

Concentration: Please refer to lot specific datasheet.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702
NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
纯化方式 affinity chromatography
species reactivity human, mouse, rat
technique(s) immunocytochemistry: suitable
immunohistochemistry: suitable (paraffin)
immunoprecipitation (IP): suitable
western blot: suitable
NCBI登记号 NP_058663
UniProt登记号 Q9EQW6
运输 wet ice

安全信息

储存分类代码 10 - Combustible liquids
WGK WGK 2
闪点(F) Not applicable
闪点(C) Not applicable

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