Anti-Nucleophosmin antibody, Rabbit monoclonal

半岛bd体育手机客户端 说明

一般描述

Nucleophosmin (NPM) is a nucleolar protein for regulating ribosome biosynthesis and centrosome duplication. The NPM gene is frequently rearranged in various types of lymphomas such as anaplastic lymphoma kinase (ALK). A C-terminal mutation occurs in acute myelogenous leukemia (AML) and prevents localization to the nucleolus, resulting in cytoplasmic distribution. NPM is frequently overexpressed in diverse solid tumors such as carcinoma of the lung and breast, colon, prostate, stomach, lymphoid and myeloid tumors.
The NPM1 (nucleophosmin 1) gene is mapped to human chromosome 5q35.1. Nucleophosmin is a predominant phospho-nucleolar protein, that is mostly, localized to the nucleus or cytoplasm.

免疫原

Synthetic peptide derived from human nucleophosmin.

特点和优势

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外形

0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES

NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
重组	expressed in proprietary host
偶联物	unconjugated
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	SP236, monoclonal
species reactivity	human (tested)
species reactivity (predicted by homology)	mouse, rat, bovine, chicken
technique(s)	flow cytometry: 1:400 immunoblotting: 1:400 immunohistochemistry: 1:100
同位素/亚型	IgG
UniProt登记号	P06748
运输	wet ice
储存温度	2-8℃
Gene Information	human ... NPM1(4869)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable