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位置: 首页> 品牌> Sigma-Aldrich> Anti-NLRP10 Antibody, clone 8H2

Anti-NLRP10 Antibody, clone 8H2

品牌
Sigma-Aldrich
货号
MABC293
规格纯度
clone 8H2, from rat
价格
6190.47 *本价格含增值税费
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数量
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半岛bd体育手机客户端 名称:
Anti-NLRP10 Antibody, clone 8H2
NACHT, LRR and PYD domains-containing protein 10, Nucleotide-binding oligomerization domain protein 8
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

NACHT, LRR and PYD domains-containing protein 10 (NLRP10) is also called Nucleotide-binding oligomerization domain protein 8. NLRP10 has anti-inflammatory activity and plays a role in immune response against infections from bacteria including C.albicans by contributing to proinflammatory cytokine release. NLRP10 is widely expressed with the highest levels found in heart, brain and skeletal muscle, as well as liver, colon, dermis and epidermis.

免疫原

Recombinant protein corresponding to human NLRP10.

应用

Research Sub Category
Apoptosis - Additional
Immunocytochemistry Analysis: A representative lot from an independent laboratory detected NLRP10 in Flag-tagged NRLP10 transfected HeLa cells (Lautz, K., et al. (2012). Cell Microbiol. 14(10:1568-1583.).

Western Blotting Analysis: A representative lot from an independent laboratory detected NLRP10 primary epidermal fibroblasts transfected with a non-targeting control siRNA, and demonstrated a loss of signal in primary epidermal fibroblasts transfected with NLRP10-specific RNA (Lautz, K., et al. (2012). Cell Microbiol. 14(10:1568-1583.).

Flow Cytometry Analysis: 4 ?g from a representative lot detected NLRP10 in 1X10E6 HeLa and Jurkat cells.
Anti-NLRP10 Antibody, clone 8H2 is a highly specific rat monoclonal antibody, that targets NLRP10 & has been tested in western blotting, Flow Cytometry & ICC.
Research Category
Apoptosis & Cancer

质量

Evaluated by Western Blotting in A431 cell lysate.

Western Blotting Analysis: 1 mg/mL of this antibody detected NLRP10 in 10 ?g of A431 cell lysate.

目标描述

~72 kDa observed

外形

Purified rat monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Format: Purified
Protein G Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
A431 cell lysate

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702
NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 100
生物来源 rat
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 8H2, monoclonal
species reactivity human
technique(s) flow cytometry: suitable
immunocytochemistry: suitable
western blot: suitable
同位素/亚型 IgG2aκ
NCBI登记号 NP_789791
UniProt登记号 Q86W26
运输 wet ice

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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