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位置: 首页> 品牌> Sigma-Aldrich> NF-κ-B1 p84/NF-κ-B1 p98

Anti-NF-κB p105 antibody produced in rabbit

NF-κ-B1 p84/NF-κ-B1 p98

品牌
Sigma-Aldrich
货号
SAB4501991
规格纯度
affinity isolated antibody
价格
5045.46 *本价格含增值税费
促销
服务
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  • 增值税票
数量
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半岛bd体育手机客户端 名称:
Anti-NF-κB p105 antibody produced in rabbit
EBP-1
NF-κ-B1 p84/NF-κ-B1 p98
NFKB1
DNA-binding factor KBF1
NFkB-p50
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Anti-NF-κB p105 Antibody detects endogenous levels of total NF-κB p105 protein.
The gene NFκB1(nuclear factor κ B subunit 1) is mapped to human chromosome 4q24. It codes for NF-κB p105/p50 isoforms.

免疫原

The antiserum was produced against synthesized peptide derived from human NF-kappaB p105/p50.

Immunogen Range:874-923

生化/生理作用

NF-κB (nuclear factor κ B subunit 1) is an important transcription factor that regulates the process of apoptosis, immune response and cell-growth control genes. It is associated with a number of human disorders including inflammatory diseases and cancers. NF-κB signaling cascade is known to be stimulated by many genotoxic stresses and also DNA damage. NF-κB is involved in bone metabolism. Downregulation of NF-κB mediates GPER (G-protein coupled estrogen receptor) specific agonist G-1 induced EMT (epithelial mesenchymal transition) suppression. Thereby, it prevents the motility of triple-negative breast cancer cellsin vitro.

特点和优势

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外形

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 antigen 105 kDa
species reactivity human
浓度 ~1 mg/mL
technique(s) ELISA: 1:10000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI登记号 P19838
UniProt登记号 P19838
运输 wet ice
储存温度 ?20℃
Gene Information human ... NFKB1(4790)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK nwg
闪点(F) Not applicable
闪点(C) Not applicable

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