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Anti-NCSTN antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB1410419
规格纯度
purified immunoglobulin, buffered aqueous solution
价格
5045.46 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
-+
半岛bd体育手机客户端 名称:
Anti-NCSTN antibody produced in rabbit
APH2
KIAA0253
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

This gene encodes a Type I transmembrane glycoprotein that is an integral component of the multimeric gamma-secretase complex. The encoded protein cleaves integral membrane proteins, including Notch receptors and beta-amyloid precursor protein, and may be a stabilizing cofactor required for gamma-secretase complex assembly. The cleavage of beta-amyloid precursor protein yields amyloid beta peptide, the main component of the neuritic plaque and the hallmark lesion in the brains of patients with Alzheimer′s disease; however, the nature of the encoded protein′s role in Alzheimer′s disease is not known for certain. Alternatively spliced transcript variants have been described, but their full-length nature has not been determined. (provided by RefSeq)

免疫原

NCSTN (AAH47621.1, 1 a.a. ~ 689 a.a) full-length human protein.

Sequence
MDFNLILESLCRGNSVERKIYIPLNKTAPCVRLLNATHQIGCQSSISGDTGVIHVVEKEEDLQWVLTDGPNPPYMVLLESKHFTRDLMEKLKGRTSRIAGLAVSLTKPSPASGFSPSVQCPNDGFGVYSNSYGPEFAHCREIQWNSLGNGLAYEDFSFPIFLLEDENETKVIKQCYQDHNLSQNGSAPTFPLCAMQLFSHMHAVISTATCMRRSSIQSTFSINPEIVCDPLSDYNVWSMLKPINTTGTLKPDDRVVVAATRLDSRSFFWNVAPGAESAVASFVTQLAAAEALQKAPDVTTLPRNVMFVFFQGETFDYIGSSRMVYDMEKGKFPVQLENVDSFVELGQVALRTSLELWMHTDPVSQKNESVRNQVEDLLATLEKSGAGVPAVILRRPNQSQPLPPSSLQRFLRARNISGVVLADHSGAFHNKYYQSIYDTAENINVSYPEWLSPEEDLNFVTDTAKALADVATVLGRALYELAGGTNFSDTVQADPQTVTRLLYGFLIKANNSWFQSILRQDLRSYLGDGPLQHYIAVSSPTNTTYVVQYALANLTGTVVNLTREQCQDPSKVPSENKDLYEYSWVQGPLHSNETDRLPRCVRSTARLARALSPAFELSQWSSTEYSTWTESRWKDIHARIFLIASKELELITLTVGFGILIFSLIVTYCINAKADVLFIAPREPGAVSY

外形

Solution in phosphate buffered saline, pH 7.4

基本信息

NACRESNA.41

半岛bd体育手机客户端 性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量antigen 76.7 kDa
species reactivityhuman, mouse
technique(s)western blot: 1 μg/mL
NCBI登记号BC047621
UniProt登记号Q92542
运输dry ice
储存温度−20℃
Gene Informationhuman ... NCSTN(23385)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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