Anti-NANOS2 Antibody

半岛bd体育手机客户端 说明

一般描述

Nanos homolog 2 (NANOS2) is a zinc-finger containing, RNA-binding protein belonging to the nanos family. NANOS2 plays an important role in the sexual differentiation of germ cells by promoting the male fate but suppressing the female fate. It has been implicated in germ cell development in both invertebrates and vertebrates. Unlike NANOS1, whose expression in mice is dispensable, the NANOS2 and NANOS3 proteins are required for germ cell development. NANOS2-null primordial germ cells (PGCs) die only in the male gonads and show no defects in females, while NANOS3-null PGCs are lost during the migration stage regardless of sex.

特异性

This antibody recognizes the N-terminus of NANOS2.

免疫原

KLH-conjugated linear peptide corresponding to the N-terminus of human NANOS2.

应用

Detect Nanos homolog 2 using this rabbit polyclonal antibody, Anti-NANOS2 Antibody validated for use in western blotting, IHC & Immunofluorescence.
Immunohistochemistry Analysis: 2.5 ?g/mL from a representative lot detected NANOS2 in human brain tissue.

Immunofluorescence Analysis: 20 ?g/mL from a representative lot detected NANOS2 in human testis cells.

质量

Evaluated by Western Blotting in rat brain tissue.

Western Blotting Analysis: 2 ?g/mL of this antibody detected NANOS2 in 15 ?g of rat brain tissue.

目标描述

~15 kDa observed

外形

Antigen Affinity Purified

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss	32160702
NACRES	NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
纯化方式	affinity chromatography
species reactivity	human, rat
technique(s)	immunofluorescence: suitable immunohistochemistry: suitable western blot: suitable
UniProt登记号	P60321
运输	wet ice

安全信息

储存分类代码	10 - Combustible liquids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable