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Anti-MYCL antibody produced in rabbit

品牌
Sigma-Aldrich
货号
HPA063132
规格纯度
Prestige Antibodies?Powered by Atlas Antibodies, affinity isolated antibody
价格
6389.73 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
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半岛bd体育手机客户端 名称:
Anti-MYCL antibody produced in rabbit
bHLHe38
MYCL1
LMYC
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

The MYCL proto-oncogene, bHLH transcription factor gene is mapped to the human chromosome 1p34.2 and encodes a nuclear phosphoprotein. The encoded protein belongs to the MYC family.

免疫原

v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog

应用

All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry.

The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit sigma.com/prestige.

生化/生理作用

The proto-oncogene, bHLH transcription factor (MYCL) regulates the expression of the target genes. It is associated with cell proliferation, differentiation, and apoptosis. The MYCL gene is a proto-oncogene, overexpressed in few malignancies. Single-nucleotide polymorphism (SNP) of MYCL is observed in many cancers. MYCL SNP might serve as a potential marker for gastric cancer.

特点和优势

Prestige Antibodies?are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies?to other proteins are due to a thorough selection of antigen regions, affinity purification, and stringent selection. Prestige antigen controls are available for every corresponding Prestige Antibody and can be found in the linkage section.

Every Prestige Antibody is tested in the following ways:

  • IHC tissue array of 44 normal human tissues and 20 of the most common cancer type tissues.
  • Protein array of 364 human recombinant protein fragments.

联系

Corresponding Antigen APREST90015.

外形

Solution in phosphate buffered saline, pH 7.2, containing 40% glycerol and 0.02% sodium azide.

法律信息

Prestige Antibodies is a registered trademark of sigma-aldrich Co. LLC

基本信息

人类蛋白质图谱编号 HPA063132 Human Protein Atlas characterization data

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
半岛bd体育手机客户端 线 Prestige Antibodies?Powered by Atlas Antibodies
形式 buffered aqueous glycerol solution
species reactivity human
technique(s) immunoblotting: 0.04-0.4 μg/mL
immunofluorescence: 0.25-2 μg/mL
免疫原序列 FELVPSPPTSPPWGLGPGAGDPAPGIGPPEPWPGGCTGDEAESRGHSKGWGRNYAS
UniProt登记号 P12524
运输 wet ice
储存温度 ?20℃
Gene Information human ... MYCL(4610)

安全信息

危险分类 Eye Irrit. 2 - Skin Irrit. 2
储存分类代码 10 - Combustible liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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