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位置: 首页> 品牌> Sigma-Aldrich> Anti-MUC13 Antibody, clone 2E11.1

Anti-MUC13 Antibody, clone 2E11.1

品牌
Sigma-Aldrich
货号
MABC209
规格纯度
clone 2E11.1, from mouse
价格
6022.61 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
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半岛bd体育手机客户端 名称:
Anti-MUC13 Antibody, clone 2E11.1
Mucin-13, MUC-13, Down-regulated in colon cancer 1
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Mucin-13 (MUC-13) is also called Down-regulated in colon cancer 1 (DRCC1). MUC-13 is an epithelial and hemopoietic transmembrane mucin that is likely involved in cell signaling. MUC-13 is highly expressed in epithelial tissues (especially in gastrointestinal and respiratory tracts) as well as kidney, small intestine, appendix and stomach.

免疫原

Epitope: This antibody recognizes the cytoplasmic domain within the Beta subunit of MUC-13.
GST-tagged recombinant protein corresponding to the cytoplasmic domain of human MUC-13.

应用

Research Sub Category
Apoptosis - Additional
Western Blotting Analysis: 0.5 ?g/mL from a representative lot detected MUC-13 in 10 ?g of human kidney tissue lysate.

Immunohistochemistry Analysis: a 1:500 dilution from a representative lot detected MUC-13 in human ilium tissues.
Research Category
Apoptosis & Cancer
Detect Mucin using this mouse monoclonal antibody, Anti-MUC13 Antibody, clone 2E11.1 validated for use in western blotting & IHC (Paraffin).

质量

Evaluated by Western Blotting in human small intestine tissue lysate.

Western Blotting Analysis: 0.5 ?g/mL of this antibody detected MUC-13 in 10 ?g of human small intestine tissue lysate.

目标描述

~33 and ~60 kDa observed. Swiss-Prot describes a molecular weight of ~55 kDa Due post-translational modification, this protein is cleaved resulting in beta subunit (~33 kDa) and an alpha subunit (Williams, S. J., et al. (2001). J Biol Chem. 276(21):18327-18336. Maher, D. M., et al. (2011). Mol Cancer Res. 9(5):531-537.). Uncharacterized band(s) may be observed in some cell lysates.

外形

Format: Purified
Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Protein G Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702
NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 100
生物来源 mouse
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 2E11.1, monoclonal
species reactivity human, rat
technique(s) immunohistochemistry: suitable (paraffin)
western blot: suitable
同位素/亚型 IgG2aκ
NCBI登记号 NP_149038
UniProt登记号 Q9H3R2
运输 wet ice
Gene Information human ... MUC13(56667)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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