Anti-MUC1 antibody produced in rabbit

半岛bd体育手机客户端 说明

一般描述

This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2011]

免疫原

A synthesized peptide derived from human MUC1

外形

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
antibody product type	primary antibodies
克隆	monoclonal
形式	liquid
species reactivity	mouse, human
浓度	0.11 mg/mL
technique(s)	western blot: 1:500-1:2000
UniProt登记号	P15941
运输	wet ice
储存温度	?20℃
Gene Information	human ... MUC1(4582)

安全信息

闪点(F)	Not applicable
闪点(C)	Not applicable