半岛bd体育手机客户端 说明
免疫原
Synthetic peptide directed towards the N terminal region of human MTHFD2
应用
Anti-MTHFD2 antibody produced in rabbit is suitable for western blotting at a concentration of 1.25μg/ml.
生化/生理作用
MTHFD2 encodes a mitochondrial bifunctional enzyme methylenetetrahydrofolate dehydrogenase/cyclohydrolase with NAD-dependent methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase domain. Decrease in MTHFD2 expression leads to impairment of cell migration and invasion into extracellular matrix and reduces the cell fraction with a high CD44 expression. It facilitates the regulation of breast cancer cell migration and invasion.
序列
Synthetic peptide located within the following region: LPLPEHIDERRICNAVSPDKDVDGFHVINVGRMCLDQYSMLPATPWGVWE
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
NACRES | NA.41 |
半岛bd体育手机客户端 性质
生物来源 | rabbit |
质量水平 | 100 |
偶联物 | unconjugated |
抗体形式 | IgG fraction of antiserum |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
分子量 | 35 kDa |
species reactivity | bovine, guinea pig, horse, rat, rabbit, human, dog, mouse |
浓度 | 0.5 mg - 1 mg/mL |
technique(s) | western blot: suitable |
NCBI登记号 | NP_001035499 |
UniProt登记号 | P13995 |
运输 | wet ice |
储存温度 | ?20℃ |
Gene Information | human ... MTHFD2(10797) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich