半岛bd体育手机客户端 说明
免疫原
MTCH2 antibody was raised against a 15 amino acid peptide near the amino terminus of human MTCH2.
特点和优势
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目标描述
Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. MTCH2 is a member of the mitochondrial carrier protein family that catalyze the exchange of substrates across the inner mitochondrial membrane and is targeted by Bid, a pro-apoptotic Bcl-2 family member, in response to apoptotic signals, suggesting that MTCH2 may play a key role in the mitochondrial apoptosis pathway.
联系
The action of this antibody can be blocked using blocking peptide SBP3500013.
外形
Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.
基本信息
NACRES | NA.41 |
半岛bd体育手机客户端 性质
生物来源 | rabbit |
质量水平 | 100 |
偶联物 | unconjugated |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
species reactivity | mouse, human |
technique(s) | immunofluorescence: suitable immunohistochemistry: suitable indirect ELISA: suitable western blot: suitable |
NCBI登记号 | AAD52647 |
UniProt登记号 | Q791V5 |
运输 | dry ice |
储存温度 | ?20℃ |
Gene Information | mouse ... Mtch2(56428) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich