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Anti-MSH3 (center) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB1300711
规格纯度
saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution
价格
5045.46 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
Anti-MSH3 (center) antibody produced in rabbit
Mismatch repair protein 1
Anti-DNA mismatch repair protein Msh3
Anti-MRP1
Anti-Divergent upstream protein
Anti-DUP
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

MSH3 is a component of the post-replicative DNA mismatch repair system (MMR). THis protein heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion-deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, it forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.

免疫原

MSH3 (NP_002430, 464-497)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human MSH3.

外形

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
偶联物 unconjugated
抗体形式 saturated ammonium sulfate (SAS) precipitated
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
species reactivity human
technique(s) indirect ELISA: 1:1000
western blot: 1:100-1:500
NCBI登记号 NP_002430
UniProt登记号 P20585
运输 dry ice
储存温度 ?20℃
Gene Information human ... MSH3(4437)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK nwg
闪点(F) Not applicable
闪点(C) Not applicable

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