Anti-MRP2 Antibody, CT, clone M2 III-6

半岛bd体育手机客户端 说明

特异性

This antibody reacts with an internal epitope of MRP2, a 190-200 kDa transmembrane protein previously known as the canalicular multi-organic anion transporter (cMOAT). MRP2 is a member of the MRP family of multidrug resistance related proteins, and MRP2 over expression has been observed in a subset of cisplatin resistant cell lines. This antibody does not cross-react with the human MDR1, MRP1, MRP3 or MRP5 gene products.

免疫原

Bacterial fusion protein of MRP2 containing the 202-aa C-terminal end
Epitope: C-terminus

应用

Research Sub Category
Toxicology & Drug Resistance
Western blotting: 1:20 - 1:50 with anti-mouse HRP

Immunocytochemistry: 1:20 - 1:50 on acetone fixed cytospin preparations

Immunohistochemistry: 1:20 on acetone fixed frozen tissue sections; 1:20 on formaldehyde-fixed paraffin-embedded tissues (pretreat with 0.01M citrate, pH 6.0, in dH2O at 100?C for 5 minutes, repeated 3 times)

Optimal working dilutions must be determined by end user.
Detect MRP2 using this Anti-MRP2 Antibody, C-terminus, clone M2 III-6 validated for use in WB, IC, IH, IH(P).
Research Category
Metabolism

外形

Liquid containing 0.7% BSA and 0.1% sodium azide.

储存及稳定性

Maintain refrigerated at 2-8°C for up to 6 months. For long-term storage store at -20°C.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss	32160702
NACRES	NA.41

半岛bd体育手机客户端 性质

质量水平	300
生物来源	mouse
抗体形式	culture supernatant
antibody product type	primary antibodies
克隆	M2 III-6, monoclonal
species reactivity	human
manufacturer/tradename	Chemicon?
technique(s)	immunocytochemistry: suitable immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable western blot: suitable
同位素/亚型	IgG2a
NCBI登记号	NM_000392.2
UniProt登记号	Q92887
运输	wet ice

安全信息

储存分类代码	10 - Combustible liquids
WGK	WGK 2