Anti-MMP-13 Antibody, clone LIPCO IID1

半岛bd体育手机客户端 说明

特异性

It recognizes proteins of ~60 kDa and ~48 kDa which are identified as pro (latent) and activate forms of matrix metalloproteinase-13 (MMP-13; also known as Collagenase-3). Antibody shows no cross-reactivity with the pro and active forms of other MMPs. Human collagenase-3 (MMP13) is a recently identified member of the matrix metalloproteinase (MMP) family that is expressed in breast carcinomas and in articular cartilage from arthritic patients. The MMP-13 gene has been isolated and characterized. This gene is composed of 10 exons and 9 introns and spans over 12.5 kb. The overall organization of the collagenase-3 gene is similar to that of other MMP genes clustered at chromosome 11q22, including fibroblast collagenase (MMP-1), matrilysin (MMP-7), and macrophage metalloelastase (MMP-12), but is more distantly related to genes coding for stromelysin-3 (MMP-11), gelatinase-A (MMP-2), and gelatinase-B (MMP-9), which map outside of this gene cluster.

Cellular Localization:

Cytoplasmic

免疫原

Rat MMP-13 from BC-1 cells.

应用

Research Category
Cell Structure
Western Blotting (Lyons, 1991; Lyons, 1993): 1:200-1:400 at room temperature for 2 hours.

Immunofluorescence

Optimal working dilutions must be determined by end user.
Anti-MMP-13 Antibody, clone LIPCO IID1 is an antibody against MMP-13 for use in WB.
Research Sub Category
MMPs & TIMPs

外形

Format: Purified

储存及稳定性

Maintain at 2-8°C in undiluted aliquots for up to 12 months.

分析说明

Control
POSITIVE CONTROL: Conditioned, serum-free medium from (PMA-treated) rat fibrosarcoma cells or rat keratinocyte CCL-4.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss	32160702
NACRES	NA.41

半岛bd体育手机客户端 性质

质量水平	100
生物来源	mouse
抗体形式	purified antibody
antibody product type	primary antibodies
克隆	LIPCO IID1, monoclonal
species reactivity	rat, mouse
manufacturer/tradename	Chemicon?
technique(s)	western blot: suitable
同位素/亚型	IgG1
NCBI登记号	NM_002427.2
UniProt登记号	P45452
运输	wet ice
Gene Information	human ... MMP13(4322)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable