半岛bd体育手机客户端 说明
一般描述
Metabotropic glutamate receptor 5 (mGluR5) is a member of the G-protein coupled receptor family and functions as a receptor for glutamate. mGluR5 activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current.
免疫原
GST-tagged recombinant protein corresponding to human mGluR5.
应用
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected mGluR5 in normal human brain tissue.
Detect mGluR5 using this mouse monoclonal antibody, Anti-mGluR5 Antibody, clone 11D9.1 validated for use in western blotting & IHC.
质量
Evaluated by Western Blotting in rat brain micropreparation tissue lysate.
Western Blotting Analysis: 1.0 ?g/mL of this antibody detected mGluR5 in 10 ?g of rat brain micropreparation tissue lysate. The lysate was not boiled during preperation for western blotting.
目标描述
~150 kDa observed. The calculated molecular weight is 130 kDa, however mGluR5 has been shown as a ~150 kDa band in western blots (Romano, C., et al. (1996). J Biol Chem. 271(45):28612-28616).
外形
Protein G Purified
Format: Purified
分析说明
Control
Rat brain micropreparation tissue lysate
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
半岛bd体育手机客户端 性质
质量水平 | 100 |
生物来源 | mouse |
抗体形式 | purified immunoglobulin |
antibody product type | primary antibodies |
克隆 | 11D9.1, monoclonal |
species reactivity | rat, human |
technique(s) | immunohistochemistry: suitable western blot: suitable |
同位素/亚型 | IgG2bκ |
NCBI登记号 | NP_000833 |
UniProt登记号 | P41594 |
运输 | wet ice |
Gene Information | human ... GRM5(2915) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich