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位置: 首页> 品牌> Sigma-Aldrich> Anti-Lysyl Oxidase (LOX) Antibody

Anti-Lysyl Oxidase (LOX) Antibody

品牌
Sigma-Aldrich
货号
ABT112
规格纯度
from rabbit, purified by affinity chromatography
价格
6022.61 *本价格含增值税费
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数量
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半岛bd体育手机客户端 名称:
Anti-Lysyl Oxidase (LOX) Antibody
Protein-lysine 6-oxidase, Lysyl oxidase
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Lysyl Oxidase (Protein-lysine 6-oxidase; LOX) is a member of the lysyl oxidase family and a product of the LOX gene. Lysyl oxidase is an extracellular-matrix oxidative enzyme characterized by its C-terminal LOX catalytic domain. In the presence of copper, lysyl oxidase removes amine groups from lysine residues of target substrates which include precursors of collagen and elastin. This deamination reaction produces reactive lysine residues which can then interact with similarly activated species to form covalent cross-links. Lysyl oxidase is found predominantly in the kidney, pancreas, heart, skeletal muscle, and placenta. Defective lysyl oxidase proteins play a role in cutis laxa autosomal recessive type 1 condition. Other studies have also suggested that lysyl oxidase may also be involved in intracellular signaling and may function as a tumor suppressor.

免疫原

KLH-conjugated linear peptide corresponding to Lysyl Oxidase (LOX).

应用

Anti-Lysyl Oxidase (LOX) Antibody is an antibody against Lysyl Oxidase (LOX) for use in Western Blotting, IHC(P).
Immunohistochemistry Analysis: A 1:100 dilution from a representative lot detected Lysyl Oxidase (LOX) in adenocarcinoma cells of human prostate tissues.

质量

Evaluated by Western Blot in NIH/3T3 nuclear extract.

Western Blot Analysis: A 1:1,000 dilution of this antibody detected Lysyl Oxidase (LOX) in 10 ?g of NIH/3T3 nuclear extract.

目标描述

~46 kDa observed

外形

Affinity purified

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702
NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
纯化方式 affinity chromatography
species reactivity human, mouse
species reactivity (predicted by homology) rat (based on 100% sequence homology)
technique(s) immunohistochemistry: suitable (paraffin)
western blot: suitable
NCBI登记号 NP_002308.2
UniProt登记号 P28300
运输 wet ice

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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