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位置: 首页> 品牌> Sigma-Aldrich> Anti-Lymphoid-specific helicase (SMARCA6) Antibody, clone 2G7.1

Anti-Lymphoid-specific helicase (SMARCA6) Antibody, clone 2G7.1

品牌
Sigma-Aldrich
货号
MABE421
规格纯度
clone 2G7.1, from mouse
价格
5688.25 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
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半岛bd体育手机客户端 名称:
Anti-Lymphoid-specific helicase (SMARCA6) Antibody, clone 2G7.1
Lymphoid-specific helicase, Proliferation-associated SNF2-like protein, SWI/SNF2-related matrix-associated actin-dependent regulator of chromatin subfamily A member 6
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

A member of the SNF2 family of chromatin remodeling proteins, Lymphoid-specific helicase (HELLS, also known as Lsh) assumes various roles in normal development, survival, de novo or maintenance DNA methylation, gene silencing, and heterochromatin formation and organization. It is shown to serve as cancer progression marker in conjunction with CEP55 and FOXM1 for the detection of head and neck squamous cell carcinoma (HNSCC). It is also reported that expression of Lsh is crucial for meiotic progression in mouse spermatocytes. Lsh is shown to directly associate with the 5′ DMR of the Cdkn1c promoter, and thereby regulate its gene expression. Additionally, Lsh is reported as a regulator of repressive chromatin at retrotransposons, and is demonstrated to mediate the silencing of stem cell-specific genes such as Oct4.

免疫原

GST-tagged recombinant protein corresponding to human Lymphoid-specific helicase (SMARCA6).

应用

Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Lymphoid-specific helicase (SMARCA6) in human placenta tissue.
Research Sub Category
Signaling Neuroscience
This Anti-Lymphoid-specific helicase (SMARCA6) Antibody, clone 2G7.1 is validated for use in western blotting & IHC for the detection of Lymphoid-specific helicase (SMARCA6).
Research Category
Epigenetics & Nuclear Function

质量

Evaluated by Western Blotting in human thymus tissue lysate.

Western Blotting Analysis: 1.0 ?g/mL of this antibody detected Lymphoid-specific helicase (SMARCA6) in 10 ?g of human thymus tissue lysate.

目标描述

~97 kDa observed

外形

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Format: Purified
Protein G Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702
NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 100
生物来源 mouse
抗体形式 purified antibody
antibody product type primary antibodies
克隆 2G7.1, monoclonal
species reactivity human
technique(s) immunohistochemistry: suitable
western blot: suitable
同位素/亚型 IgG1κ
NCBI登记号 NP_060533
UniProt登记号 Q9NRZ9
运输 wet ice

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

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