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位置: 首页> 品牌> Sigma-Aldrich> Anti-LRRFIP1 Antibody

Anti-LRRFIP1 Antibody

品牌
Sigma-Aldrich
货号
ABT406
规格纯度
from rabbit, purified by affinity chromatography
价格
5854.74 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Anti-LRRFIP1 Antibody
Leucine-rich repeat flightless-interacting protein 1, LRR FLII-interacting protein 1, GC-binding factor 2, TAR RNA-interacting protein
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Leucine-rich repeat flightless-interacting protein 1 (LRR FLII-interacting protein 1), also known as GC-binding factor 2 or TAR RNA-interacting protein, and encoded by the gene name LRRFIP1 or GCF2 or TRIP, is a transcriptional repressor that mainly plays a cytoskeletal role. LRRFIP1 is primarily localized in the cytoplasm and preferentially binds to GC-rich dsDNA, but will also bind directly to dsRNA as well. The RNA binding domain encompasses a lysine-rich motif. LRRFIP1 interacts with the mammalian Flightless I (Fli-I) and is a key component in the cytoskeletal regulation of platelet function. LRRFIP1 and the related protein LRRFIP2 may modulate canonical WNT signaling and mediate the IRF3-induced production of type I interferon via a β-catenindependent pathway.

免疫原

KLH-conjugated synthetic peptide corresponding to human LRRFIP1.

应用

Anti-LRRFIP1 Antibody detects level of LRRFIP1 & has been published & validated for use in LRRFIP1.
Research Category
Cell Structure
Research Sub Category
Cytoskeleton

质量

Evaluated by Western Blotting in human colon tissue lysate.

Western Blotting Analysis: 1 μg/mL of this antibody detected LRRFIP1 in human colon tissue lysate.

目标描述

~85 kDa observed. Uncharacterized bands may be observed in some lysate(s). Uniprot describes 4 isoforms produced by alternative splicing ranging between ~73 kDa and ~89 kDa

外形

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Antigen Affinity Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702
NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
纯化方式 affinity chromatography
species reactivity human
technique(s) western blot: suitable
UniProt登记号 Q32MZ4
运输 wet ice
Gene Information human ... LRRFIP1(9208)

安全信息

储存分类代码 10 - Combustible liquids
WGK WGK 2
闪点(F) Not applicable
闪点(C) Not applicable

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