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位置: 首页> 品牌> Sigma-Aldrich> Anti-LRP6 (C-term T1546) antibody produced in rabbit

Anti-LRP6 (C-term T1546) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB1300012
规格纯度
IgG fraction of antiserum, buffered aqueous solution
价格
4618.16 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Anti-LRP6 (C-term T1546) antibody produced in rabbit
Anti-LDL receptor-related protein 6
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

LRP6 is essential for the Wnt/beta catenin signaling pathway, probably by acting as a coreceptor together with Frizzled for Wnt. It is a specific, high-affinity receptor for DKK1 and DKK2, but not DKK3. The interaction with DKK1 blocks LRP6-mediated Wnt/beta catenin signaling via LRP6 removal via Kremen proteins-mediated endocytosis.

免疫原

LRP6 (NP_002327, 1536-1570)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human LRP6.

外形

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
偶联物 unconjugated
抗体形式 IgG fraction of antiserum
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
species reactivity human
technique(s) immunohistochemistry: 1:50-1:100
indirect ELISA: 1:1000
western blot: 1:100-1:500
NCBI登记号 NP_002327
UniProt登记号 O75581
运输 dry ice
储存温度 ?20℃
Gene Information human ... LRP6(4040)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK nwg
闪点(F) Not applicable
闪点(C) Not applicable

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