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位置: 首页> 品牌> Sigma-Aldrich> Anti-Lipocalin-2 Antibody, clone PA348-26.3.5

Anti-Lipocalin-2 Antibody, clone PA348-26.3.5

品牌
Sigma-Aldrich
货号
MABN481
规格纯度
clone PA348-26.3.5, from mouse
价格
5426.21 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
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半岛bd体育手机客户端 名称:
Anti-Lipocalin-2 Antibody, clone PA348-26.3.5
ngal, neutrophil lipocalin, siderocalin, Neutrophil gelatinase-associated lipocalin, NGAL, 25 kDa alpha-2-microglobulin-related subunit of MMP-9, Lipocalin-2, Oncogene 24p3, Siderocalin LCN2, p25
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Lipocalin-2 (LCN2) (also known as Neurophil Gelatinase-Associated Lipocalin or NGAL) belongs to a superfamily of lipocalins, a collection of small, diversely functional, extracellular proteins. Lipocalin-2 is secreted from neutrophil granules in three different forms: a monomer of 25 kDa, a disulfide-linked homodimer at 46 kDa, and a disulfide-linked heterodimer with MMP-9 at 135-kDa. It is widely known to induce development of kidney epithelia, to bind and traffic iron, and to act as a molecular signal under inflammatory conditions, such as Crohn’s Disease. Multiple carcinoma studies have also shown elevated expression levels of Lipocalin-2 in several different human tumors affecting such organs as colon, lung, breast, ovaries, and pancreas. Additionally, there has been great interest in this protein as a possible marker for onset of Acute Kidney Injury following cardiac surgery, the progression of Chronic Kidney Disease (CKD), and the survival chances of patients with Chronic Heart Failure (CHF).

免疫原

Recombinant protein corresponding to human Lipocalin-2.

应用

Immunohistochemistry Analysis: A 1:2,000 dilution from a representative lot detected Lipoacalin-2 in human bone marrow and stomach tissue lysate.

ELISA Analysis: A representative lot from an independent laboratory detected Lipocalin-2 in indirect ELISA.
Research Category
Neuroscience
Detect Lipocalin using this mouse monoclonal antibody, Anti-Lipocalin-2 Antibody, clone PA348-26.3.5 validated for use in western blotting, IHC & ELISA.
Research Sub Category
Neurodegenerative Diseases

质量

Evaluated by Western Blotting in human lung tissue lysate.

Western Blotting Analysis: 1 ?g/mL of this antibody detected Lipocalin-2 in 10 ?g of human lung tissue lysate.

目标描述

~23 kDa observed. Uncharacterized band(s) may be observed in some cell lysates.

外形

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Format: Purified
Protein G Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702
NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 100
生物来源 mouse
抗体形式 purified antibody
antibody product type primary antibodies
克隆 PA348-26.3.5, monoclonal
species reactivity human
technique(s) ELISA: suitable
immunohistochemistry: suitable
western blot: suitable
同位素/亚型 IgG1κ
NCBI登记号 NP_005555.1
UniProt登记号 P80188
运输 wet ice

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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