您好,欢迎来到半岛电竞官方网址 ! [ 登录] [ 免费注册]
半岛电竞官方网址
位置: 首页> 品牌> Sigma-Aldrich> Anti-Lin28 antibody produced in rabbit

Anti-Lin28 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB4300679
规格纯度
affinity isolated antibody
价格
4618.16 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
Anti-Lin28 antibody produced in rabbit
Anti-CSDD1
Anti-LIN28A
Anti-LIN-28
Anti-ZCCHC1
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

The Lin28 (lin-28 homolog A) gene encodes RNA-binding protein, and is located on human chromosome 1p36.

The antibody detects endogenous levels of total Lin28 protein.

免疫原

Peptide sequence around aa. 1-5 (M-G-S-V-S), according to the protein NP_078950.1

生化/生理作用

The Lin28 (lin-28 homolog A) protein participates in several biological processes like development, reprogramming, differentiation, pluripotency and glucose metabolism.{19, 20} It plays an important role in immunity.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

目标描述

Acts as a ′translational enhancer′, driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing the mRNAs. Binds IGF2 mRNA, MYOD1 mRNA, ARBP/36B4 ribosomal protein mRNA and its own mRNA. Essential for skeletal muscle differentiation program through the translational up-regulation of IGF2 expression. Acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7), a miRNA precursor. Acts by binding pre-let-7 and recruiting ZCCHC11/TUT4 uridylyltransferase, leading to the terminal uridylation of pre-let-7. Uridylated pre-let-7 miRNAs fail to be processed by Dicer and undergo degradation. Degradation of pre-let-7 in embryonic stem (ES) cells contributes to the maintenance of ES cells.

外形

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 ~26 kDa
species reactivity mouse, human, rat
浓度 1 mg/mL
technique(s) western blot: 1:500-1:1000
同位素/亚型 IgG
免疫原序列 (M-G-S-V-S)
NCBI登记号 NM_024674.4
运输 wet ice
储存温度 ?20℃
Gene Information human ... Lin28(79727)

安全信息

储存分类代码 10 - Combustible liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

推荐半岛bd体育手机客户端
Baidu
map