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位置: 首页> 品牌> Sigma-Aldrich> Anti-KLRG1 Antibody (mouse), FITC, clone 2F1

Anti-KLRG1 Antibody (mouse), FITC, clone 2F1

品牌
Sigma-Aldrich
货号
MABF468
规格纯度
clone 2F1, 0.5 mg/mL, from hamster(Syrian)
价格
3841.74 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
Anti-KLRG1 Antibody (mouse), FITC, clone 2F1
Killer cell lectin-like receptor subfamily G member 1, Mast cell function-associated antigen 2F1
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

This golden syrian hamster monoclonal antibody Anti-KLRG1 (mouse), FITC, clone 2F1 validated for use in IP & Flow Cytometry for the detection of KLRG1.
The 2F1 antibody reacts with mouse KLRG1 (Killer cell Lectin-like Receptor G1). This 30-38 kDa homodimeric receptor may be expressed by activated, mature NK cells and by effector/memory T cells, with potentially different roles in each cell type. KLRG1 can regulate, in an inhibitory fashion, the development and effector functions of NK cells, and is often cited as a senescence or terminal differentiation marker for T cells. Ligands for KLRG1 include members of the cadherin family of adhesion molecules, specifically N-Cadherin, E-Cadherin, and R-Cadherin. These interactions may induce bidirectional, immunosuppressive signaling in both KLRG- and Cadherin-expressing cells. A more recently identified role for KLRG1-Cadherin signaling in tissue organization, e.g. in cardiac angiogenesis, expands the function of these interactions beyond immunosuppression of immune cells. (Bouchentouf et al. 2010. J. Immunol. 185: 7014-7025).The 2F1 antibody may be used as a phenotypic marker for KLRG1 in mouse, frequently in combination with Anti-Mouse CD127 antibody (clone A7R34), for identification of effector T cell populations.

质量

The monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

Flow Cytometry Analysis: 0.5 ?g of this antibody detected KLRG1 in one million C57Bl/6 splenocytes.

外形

Size Exclusion Chromatography

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702
NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 hamster (Syrian)
质量水平 100
偶联物 FITC conjugate
抗体形式 purified antibody
antibody product type primary antibodies
克隆 2F1, monoclonal
species reactivity mouse
浓度 0.5 mg/mL
technique(s) flow cytometry: suitable
immunoprecipitation (IP): suitable
同位素/亚型 IgG
UniProt登记号 O88713
运输 wet ice

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK nwg
闪点(F) Not applicable
闪点(C) Not applicable

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