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位置: 首页> 品牌> Sigma-Aldrich> Anti-KIR2DS2 (N-terminal) antibody produced in rabbit

Anti-KIR2DS2 (N-terminal) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB2109168
规格纯度
affinity isolated antibody
价格
4813.03 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Anti-KIR2DS2 (N-terminal) antibody produced in rabbit
183ActI
NKAT5
CD158b
CU464060.1
CD158J
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response.

序列

Synthetic peptide located within the following region: ETVILQCWSDVRFEHFLLHREGKYKDTLHLIGEHHDGVSKANFSIGPMMQ

外形

Supplied at 0.5 mg/ml in phosphate-buffered saline, 0.09% sodium azide

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

半岛bd体育手机客户端 性质

生物来源 rabbit
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 32 kDa
species reactivity (predicted by homology) human
浓度 0.5 mg/mL
technique(s) western blot: 1 μg/mL
NCBI登记号 NM_012312
运输 wet ice
储存温度 ?20℃
Gene Information human ... KIR2DS2(57396)

安全信息

储存分类代码 10 - Combustible liquids
WGK nwg
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

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