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位置:首页 > 品牌 > Sigma-Aldrich > Anti-α-M (complement component 3 receptor 3 subunit)

Anti-ITGAM antibody produced in goat

品牌
Sigma-Aldrich
货号
SAB2500547
规格纯度
affinity isolated antibody, buffered aqueous solution
价格
7062.55 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
半岛bd体育手机客户端 名称:
Anti-ITGAM antibody produced in goat
Anti-CD11B
Anti-Integrin
Anti-MAC-1
Anti-CR3A
Anti-α-M (complement component 3 receptor 3 subunit)
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Integrin α M (ITGAM) is also called as cluster of differentiation 11b (CD11b) or intercellular adhesion molecule-1 (ICAM-1). It is expressed on monocytes/macrophages, natural killer cells, neutrophils and a subset of B-and T-lymphocytes. ITGAM gene is located on human chromosome 16p11.

免疫原

Peptide with sequence C-RNDGEDSYRTQ from the internal region of the protein sequence according to NP_000623.2 .

生化/生理作用

Integrin α M (ITGAM) is involved in cell activation, chemotaxis, cytotoxicity and phagocytosis. It modulates the interaction of leukemic cells with microenvironment by binding inactivated complement component 3b (iC3b), intercellular adhesion molecule (ICAM), fibrinogen, beta-glukanes, coagulation factor X etc. ITGAM is considered as a marker for myeloid-derived suppressor cells that participates in restraining antitumor immunity of the host and inducing the enlargement and drug-resistance of hematological malignant cells. D11b integrin contributes to ICAM-1-dependent AIDP patient mononuclear leukocyte adhesion.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD00240630
NACRESNA.41

半岛bd体育手机客户端 性质

质量水平100
生物来源goat
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
species reactivityhuman
technique(s)ELISA: suitable
immunofluorescence: suitable
immunohistochemistry: suitable
UniProt登记号P11215
运输dry ice
储存温度−20℃
Gene Informationhuman ... ITGAM(3684)

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable

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