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位置: 首页> 品牌> Sigma-Aldrich> Anti-Integrin αVβ5 Antibody, clone P1F6

Anti-Integrin αVβ5 Antibody, clone P1F6

Anti-Integrin αVβ5 Antibody, clone P1F6

品牌
Sigma-Aldrich
货号
MAB1961
规格纯度
clone P1F6, Chemicon?, from mouse
价格
6370.62 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
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半岛bd体育手机客户端 名称:
Anti-Integrin αVβ5 Antibody, clone P1F6
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha V chain. Alpha chain V undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.

特异性

Reacts with the human integrin alphaVbeta5.

免疫原

Human UCLA P3 cells (lung carcinoma)

应用

Research Category
Cell Structure
Research Sub Category
Integrins
Inhibition of attachment of HT29 cells to vitronectin: >1:1,000

Inhibition of attachment of carcinoma and melanoma cells to vitronectin.

Immunohistochemistry: for use on acetone or paraformaldehyde fixed tissue. (Staining of formalin-fixed tissues REQUIRES boiling tissue sections in 1mM EDTA, pH 8.0, for 10-20 min followed by cooling at RT for 20 min.)

Immunocytochemistry: 1:1500. For use on human carcinomas, normal epithelium and keratinocytes (Acetone Fixed Only).

Immunoprecipitation

FACS

EIA

Optimal working dilutions must be determined by the end user.
This Anti-Integrin αVβ5 Antibody, clone P1F6 is validated for use in FC, IC, IH, IP, FUNC for the detection of Integrin αVβ5.

外形

Format: Purified
Protein A purified
Protein A Purified mouse immunoglobulin in 20 mM sodium phosphate, 250 mM NaCl, pH. 7.6, with 0.1% sodium azide as a preservative.

储存及稳定性

Maintain for 1 year at 2–8°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

分析说明

Control
Epithelium, keratinocytes

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702
NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 100
生物来源 mouse
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 P1F6, monoclonal
species reactivity human, chicken
manufacturer/tradename Chemicon?
technique(s) flow cytometry: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
同位素/亚型 IgG1
适用性 not suitable for immunohistochemistry (Paraffin)
NCBI登记号 NM_002210.2
UniProt登记号 P06756
运输 wet ice
Gene Information human ... ITGAV(3685)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 2
闪点(F) Not applicable
闪点(C) Not applicable

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