Anti-Integrin alpha-V Antibody, clone 272-17E6 (Azide free)

半岛bd体育手机客户端 说明

一般描述

Integrin alpha-V (or CD51; vitronectin receptor subunit alpha) protein is a transmembrane receptor that mediates adhesion of cells to each other and to the extracellular matrix. Integrin receptors are activated by a variety of intracellular signals that modify its cytoplasmic domain and induce configural changes in integrin molecules thereby enabling ligand binding to the extracellular surface. An important part of this process is the binding of the actin protein, talin, to the integrin cytoplasmic domain.

免疫原

Human Placental ɑvβ3

应用

Research Category
Cell Structure
Anti-Integrin alpha-V Antibody, clone 272-17E6 (Azide free) detects level of Integrin alpha-V & has been published & validated for use in Flow Cytometry, Immunoprecipitation, Activity Assay.
Immunoprecipitation Analysis: A representative lot was used by an independent laboratory to detect Integrin alpha-V in M21 cell lysates. (Mitjans, F., et al (1995). Journal of Cell Science. 108:2825-2838.)
Research Sub Category
Adhesion (CAMs)

质量

Evaluated by Flow Cytometry in HeLa cells.

Flow Cytometry Analysis: 0.5 ?g of this antibody detected Integrin alpha-V in HeLa cells.

目标描述

116 kDa calculated

外形

Purified mouse monoclonal IgG1κ in buffer containing PBS without preservative.
Format: Purified
Protein G Purified

储存及稳定性

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

分析说明

Control
HeLa cells

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss	32160702
NACRES	NA.41

半岛bd体育手机客户端 性质

质量水平	100
生物来源	mouse
抗体形式	purified antibody
antibody product type	primary antibodies
克隆	272-17E6, monoclonal
species reactivity	human
technique(s)	activity assay: suitable flow cytometry: suitable immunoprecipitation (IP): suitable
同位素/亚型	IgG1κ
NCBI登记号	NP_001138472
UniProt登记号	P06756
运输	wet ice
Gene Information	human ... ITGAV(3685)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable