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位置: 首页> 品牌> Sigma-Aldrich> Anti-IL6 high affinity antibody, Mouse monoclonal

Anti-IL6 high affinity antibody, Mouse monoclonal

品牌
Sigma-Aldrich
货号
SAB4200733
规格纯度
clone IL6-4G1, purified from hybridoma cell culture
价格
6162.13 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
Anti-IL6 high affinity antibody, Mouse monoclonal
Anti-CTL differentiation factor (CDF)
Anti-Hybridoma growth factor
Anti-B-cell stimulatory factor 2 (BSF-2)
Anti-Interferon beta-2 (IFN-beta-2)
Anti-Interleukin-6
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Anti-IL6 high-affinity antibody, mouse monoclonal (mouse IgG1 isotype) is derived from the IL6-4G1 hybridoma, produced by the fusion of mouse NS1 myeloma cells and splenocytes from a BALB/c mouse. Interleukin-6 (IL6) is mapped on the human chromosome at 7p15.3.

特异性

Monoclonal Anti-IL6 specifically recognizes human IL6 (KD ~4 x 10-11 M as measured by the Biacore system).

免疫原

recombinant human IL6

应用

Anti-IL6 high-affinity antibody, mouse monoclonal may be used in:

  • immunoblotting
  • immunoprecipitation
  • enzyme-linked immunosorbent assay (ELISA)

生化/生理作用

Interleukin-6 (IL6) is a multifunctional cytokine that plays a wide variety of biological roles in numerous systems including the immune, nervous and endocrine systems. It is considered to perform as a primary regulator of acute and chronic inflammatory diseases. IL6 is an excellent target for clinical treatment against autoimmune disorders such as rheumatoid arthritis, juvenile idiopathic arthritis and Castleman′s disease. It is overexpressed in the pathogenesis of myeloma patients. IL6 might have elevated serum IL6 levels in patients with different kinds of malignant disease. IL6 at higher levels are also clinically implemented as biomarkers for acute coronary syndrome (ACS) , unstable angina, cardiovascular disease, heart attack and stroke.

外形

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

储存及稳定性

For continuous use, store at 2–8 ℃ for up to one month. For extended storage, freeze in working aliquots. Repeated freezing and thawing is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours.

免责声明

Unless otherwise stated in our catalog, our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses,in vitrodiagnostic uses,ex vivoorin vivotherapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 200
生物来源 mouse
抗体形式 purified from hybridoma cell culture
antibody product type primary antibodies
克隆 IL6-4G1, monoclonal
形式 buffered aqueous solution
species reactivity human
浓度 ~1.0 mg/mL
technique(s) ELISA: suitable
immunoblotting: 2-4 μg/mL using concentrated supernatant of human osteosarcoma MG-63 cells treated with IL1β
immunoprecipitation (IP): 1-2 μg/test using concentrated supernatant of human osteosarcoma MG-63 cells treated with IL1β
同位素/亚型 IgG1
UniProt登记号 P05231
运输 dry ice
储存温度 ?20℃
Gene Information human ... IL6(3569)

安全信息

储存分类代码 12 - Non Combustible Liquids
闪点(F) Not applicable
闪点(C) Not applicable

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