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位置: 首页> 品牌> Sigma-Aldrich> Anti-IL22 antibody produced in rabbit

Anti-IL22 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
AV49523
规格纯度
affinity isolated antibody
价格
6889.23 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
Anti-IL22 antibody produced in rabbit
Anti-IL-TIF
Anti-Interleukin 22
Anti-IL-21
Anti-IL-D110
Anti-IL-22
Anti-IL21
Anti-ILTIF
Anti-MGC79382
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Interleukin 22 (IL-22) belongs to the IL10 family of T-cell associated cytokines, highly expressed in αβ and γδ T cells, as well as in innate lymphoid cells. Inflammatory cells associated with the thymus, pancreas, synovium, skin, and gut secrete IL-22. The Il-22 gene is localized on human chromosome 12q15.

免疫原

Synthetic peptide directed towards the C terminal region of human IL22

应用

Anti-IL22 antibody produced in rabbit has been used in immunoblotting (1:1000).

生化/生理作用

Interleukin 22 (IL22) belongs to the interleukin 10 (IL-10) family. It is a cytokine that contributes to the inflammatory responsein vivo. IL22 cellular effects are mediated by a heterodimeric receptor made up of IL22 and IL-10Rβ. IL22 signaling mediates proliferation of epithelial cells during inflammation mainly by the activation of signal transducer and activator of transcription 1 (STAT1) and STAT3 signaling.
Interleukin 22 (IL-22) plays a key role in cell proliferation, cellular defense, and tissue regeneration, It shows potential in wound healing and to treat gastrointestinal (GI)-related illnesses. Higher levels of IL-22 is observed in systemic lupus erythematosus, vitiligo, multiple sclerosis, etc.

序列

Synthetic peptide located within the following region: CHIEGDDLHIQRNVQKLKDTVKKLGESGEIKAIGELDLLFMSLRNACI

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 20 kDa
species reactivity mouse, human, rat
浓度 0.5 mg - 1 mg/mL
technique(s) western blot: suitable
NCBI登记号 NP_065386
UniProt登记号 Q9GZX6
运输 wet ice
储存温度 ?20℃
Gene Information human ... IL22(50616)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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