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位置: 首页> 品牌> Sigma-Aldrich> ANTI-IDDM12(N-TERMINAL) antibody produced in rabbit

ANTI-IDDM12(N-TERMINAL) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB1306189
规格纯度
affinity isolated antibody, buffered aqueous solution
价格
6662.67 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
ANTI-IDDM12(N-TERMINAL) antibody produced in rabbit
Cytotoxic T-lymphocyte protein 4
CD_antigen=CD152
Cytotoxic T-lymphocyte-associated antigen 4
CD152
CTLA4
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

CTLA4 (cytotoxic T-lymphocyte associated protein 4), also known as IDDM12 or CD152 (cluster of differentiation), is a T cell receptor which belongs to the immunoglobulin (Ig) superfamily. It is expressed on the surface of T helper cells. This gene is localized to human chromosome 2q33. This protein is composed of a cytosolic domain, a transmembrane region and a V domain of 116 amino acids. Alternative splicing of IDDM12 results in membrane and soluble forms. The membrane form works as homodimers and the soluble isoforms work as monomers.

生化/生理作用

CTLA4 (cytotoxic T-lymphocyte associated protein 4) or insulin dependent diabetes mellitus 12 (IDDM12) is responsible for inhibiting T-cell proliferation and facilitates T cell apoptosis. This protein is expressed post-antigen presentation and thus, is involved in immune and autoimmune disorders. It is implicated in the pathogenesis of various T cell mediated autoimmune disorders.

外形

Supplied in PBS with 0.09% (W/V) sodium azide

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 24656 Da
species reactivity human
technique(s) immunohistochemistry: 1:50-1:100
western blot: 1:2000
NCBI登记号 NP_001032720.1
UniProt登记号 P16410
运输 wet ice
储存温度 ?20℃
Gene Information human ... CTLA4(1493)

安全信息

储存分类代码 12 - Non Combustible Liquids
闪点(F) Not applicable
闪点(C) Not applicable

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