Anti-Human IgG3 antibody, Mouse monoclonal

半岛bd体育手机客户端 说明

一般描述

Human IgG consist of four subclasses (1-4) that can be recognized by antigenic differences in their heavy chains. They constitute approximately 65, 30, 5 and 4% of the total IgG, respectively. The abundance of the different IgG subclasses in the bloodstream varies with age, IgG1 and IgG3 reach normal adult levels by 5-7 years of age while IgG2 and IgG4 levels rise more slowly, reaching adult levels at about 10 years of age.

免疫原

Human IgG3 myeloma proteins covalently coupled to polyaminostyrene (PAS) microbeads

应用

Anti-Human IgG3 antibody, mouse monoclonal has been used in indirect ELISA and immunoprecipitation.

生化/生理作用

IgG1 and IgG3 are the only subclasses capable of adherence to mononuclear phagocytes and are recognized readily by the Fc receptors on various reticulo-endothelial . IgG3 deficiency has been associated with a history of recurrent infectious, leading to chronic lung disease.

外形

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

半岛bd体育手机客户端 性质

质量水平	200
生物来源	mouse
抗体形式	purified from hybridoma cell culture
antibody product type	primary antibodies
克隆	HP-6050, monoclonal
形式	buffered aqueous solution
species reactivity	human
浓度	~1.0 mg/mL
technique(s)	immunoprecipitation (IP): 1-2.5 μg/test using Human IgG3 myeloma indirect ELISA: 0.15-0.3 μg/mL using 1 μg/ml Human IgG3 myeloma for coating
同位素/亚型	IgG1
运输	dry ice
储存温度	?20℃

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable