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位置: 首页> 品牌> Sigma-Aldrich> Anti-HLA-DMA antibody produced in rabbit

Anti-HLA-DMA antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB1408586
规格纯度
purified immunoglobulin, buffered aqueous solution
价格
5045.46 *本价格含增值税费
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数量
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半岛bd体育手机客户端 名称:
Anti-HLA-DMA antibody produced in rabbit
RING6
DMA
HLADM
D6S222E
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. (provided by RefSeq)

免疫原

HLA-DMA (NP_006111.2, 1 a.a. ~ 261 a.a) full-length human protein.

Sequence
MGHEQNQGAALLQMLPLLWLLPHSWAVPEAPTPMWPDDLQNHTFLHTVYCQDGSPSVGLSEAYDEDQLFFFDFSQNTRVPRLPEFADWAQEQGDAPAILFDKEFCEWMIQQIGPKLDGKIPVSRGFPIAEVFTLKPLEFGKPNTLVCFVSNLFPPMLTVNWQHHSVPVEGFGPTFVSAVDGLSFQAFSYLNFTPEPSDIFSCIVTHEIDRYTAIAYWVPRNALPSDLLENVLCGVAFGLGVLGIIVGIVLIIYFRKPCSGD

外形

Solution in phosphate buffered saline, pH 7.4

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
偶联物 unconjugated
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 antigen ~29.2 kDa
species reactivity human, mouse
technique(s) western blot: 1 μg/mL
NCBI登记号 NM_006120
UniProt登记号 P28067
运输 dry ice
储存温度 ?20℃
Gene Information human ... HLA-DMA(3108)

安全信息

储存分类代码 13 - Non Combustible Solids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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