Anti-HLA-A antibody produced in rabbit

半岛bd体育手机客户端 说明

一般描述

HLA-A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-A alleles have been described. [provided by RefSeq, Jul 2008]

免疫原

A synthesized peptide derived from human HLA-A

外形

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
antibody product type	primary antibodies
克隆	monoclonal
形式	liquid
浓度	0.33 mg/mL
technique(s)	immunohistochemistry: 1:50-1:200 western blot: 1:500-1:2000
UniProt登记号	P01891
运输	wet ice
储存温度	?20℃
Gene Information	human ... HLA-A(3105)

安全信息

闪点(F)	Not applicable
闪点(C)	Not applicable