Anti-HEXA (C-terminal) antibody produced in rabbit

半岛bd体育手机客户端 说明

一般描述

This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I).

免疫原

Synthetic peptide directed towards the C terminal region of human HEXA

序列

Synthetic peptide located within the following region: WKDFYIVEPLAFEGTPEQKALVIGGEACMWGEYVDNTNLVPRLWPRAGAV

外形

Supplied at 0.5 mg/ml in phosphate-buffered saline, 0.09% sodium azide

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

半岛bd体育手机客户端 性质

生物来源	rabbit
偶联物	unconjugated
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
形式	buffered aqueous solution
分子量	48 kDa
species reactivity (predicted by homology)	guinea pig, mouse, canine, horse, bovine, human, rabbit, sheep, pig
浓度	0.5 mg/mL
technique(s)	immunohistochemistry (formalin-fixed, paraffin-embedded sections): 4-8 μg/mL western blot: 1 μg/mL
NCBI登记号	NM_000520
运输	wet ice
储存温度	?20℃
Gene Information	human ... HEXA(57396)

安全信息

储存分类代码	10 - Combustible liquids
WGK	nwg
闪点(F)	Not applicable
闪点(C)	Not applicable