半岛bd体育手机客户端 说明
一般描述
GRIN2B (glutamate ionotropic receptor NMDA type subunit 2B) codes forN-methyl d-aspartate receptor subtype 2B (GluN2B). It belongs to theN-methyl-D-aspartate receptor (NMDAR) gene family. It is located on human chromosome 12p13.1.
免疫原
Peptide sequence around aa. 1472-1476 (H-V-Y-E-K), according to the protein GRIN2B.
生化/生理作用
GRIN2B (glutamate ionotropic receptor NMDA type subunit 2B) plays an important role in the growth of neurons and is highly essential for the learning and memory. GRIN2B mutation is associated with neuropsychiatric and developmental disorders like schizophrenia, Parkinson′s disease and bipolar disorder.
特点和优势
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目标描述
NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine.
外形
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| MDL编号 | MFCD00243314 |
| NACRES | NA.41 |
半岛bd体育手机客户端 性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | ~190 kDa |
| species reactivity | mouse, rat, human |
| 浓度 | 1 mg/mL |
| technique(s) | indirect immunofluorescence: 1:100-1:200 |
| 同位素/亚型 | IgG |
| 免疫原序列 | (H-V-Y-E-K) |
| NCBI登记号 | NP_000825.2 |
| UniProt登记号 | Q13224 |
| 运输 | wet ice |
| 储存温度 | ?20℃ |
| Gene Information | human ... GRIN2B(2904) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
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