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Anti-GPLD1 antibody produced in mouse

品牌
Sigma-Aldrich
货号
SAB1405888
规格纯度
purified immunoglobulin, buffered aqueous solution
价格
5045.46 *本价格含增值税费
促销
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半岛bd体育手机客户端 名称:
Anti-GPLD1 antibody produced in mouse
GPIPLDM
GPIPLD
PIGPLD
PIGPLD1
MGC22590
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Many proteins are tethered to the extracellular face of eukaryotic plasma membranes by a glycosylphosphatidylinositol (GPI) anchor. The GPI-anchor is a glycolipid found on many blood cells. The protein encoded by this gene is a GPI degrading enzyme. Glycosylphosphatidylinositol specific phospholipase D1 hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans, thereby releasing the attached protein from the plasma membrane. (provided by RefSeq)

免疫原

GPLD1 (AAH20748.1, 1 a.a. ~ 176 a.a) full-length human protein.

Sequence
MSAFRLWPGLLIMLGSLCHRGSPCGLSTHIEIGHRALEFLQLHNGRVNYRELLLEHQDAYQAGIVFPDCFYPSICKGGKFHDVSESTHWTPFLNASVHYIRENYPLPWEKDTEKLVAFLFGITSHMAADVSWHSLGLEQGFLRTMGAIDFHGSYSEAHSAGDFGTVYLHLLNFLVV

应用

Anti-GPLD1 antibody produced in mouse is suitable for western blot analysis.

生化/生理作用

GPLD1 (Glycosylphosphatidylinositol specific phospholipase D1) is only expressed in human lver. Inositol phosphate linkage in proteins anchored by phosphatidylinositol-glycans (PI-Gs) is specifically hydrolyzed by GPLD1, suggesting GPLD1 expression might influence the location and expression of PI-G-anchored proteins. Studies have reported that it might be a significant factor in process of leukemia pathogenesis.

外形

Solution in phosphate buffered saline, pH 7.4

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 100
生物来源 mouse
偶联物 unconjugated
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 antigen ~19.9 kDa
species reactivity human
technique(s) western blot: 1 μg/mL
NCBI登记号 BC020748.1
UniProt登记号 P80108
运输 dry ice
储存温度 ?20℃
Gene Information human ... GPLD1(2822)

安全信息

储存分类代码 13 - Non Combustible Solids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

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