Anti-Fox1 Antibody, clone D8F8

半岛bd体育手机客户端 说明

一般描述

Fox1, also commonly referred to as Ataxin-2-binding protein 1, is an RNA binding protein involved in the regulation of tissue-specific alternative splicing. This protein contains a highly conserved RRM (RNA recognition motif) and associates with 5′-UGCAUGU-3′ elements. This protein has been demonstrated to regulate alternative splicing of tissue specific exons and differentially spliced exons during erythropoiesis. Its alternative name, Ataxin-2-binding protein, is a result of its association with the C terminus of ataxin 2 which may contribute to the pathology of the neurogenerative disease spinocerebellar ataxia type 2 (SCA2).

免疫原

Recombinant protein corresponding to mouse Fox1.

应用

Research Category
Epigenetics & Nuclear Function
Anti-Fox1 Antibody, clone D8F8 is a Mouse Monoclonal Antibody for detection of Fox1 also known as hexaribonucleotide binding protein 1, Ataxin-2-binding protein 1 & has been validated in WB.
Research Sub Category
RNA Metabolism & Binding Proteins

质量

Evaluated by Western Blot in mouse heart tissue lysate.

Western Blot Analysis: 0.5 ?g/mL of this antibody detected Fox1 on 10 ?g of mouse heart tissue lysate.

目标描述

~55 kDa observed. Uncharacterized bands potentially due to alternative splicing have been observed at ~33 and 37 kDa

外形

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Format: Purified
Protein G

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
Mouse heart tissue lysate

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss	32160702
NACRES	NA.41

半岛bd体育手机客户端 性质

质量水平	100
生物来源	mouse
抗体形式	purified antibody
antibody product type	primary antibodies
克隆	D8F8, monoclonal
species reactivity	mouse
technique(s)	western blot: suitable
同位素/亚型	IgG1κ
NCBI登记号	NP_067452
UniProt登记号	Q9JJ43
运输	wet ice

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 2